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While misanthropes express a general dislike for humanity on the whole, they generally have normal relationships with specific individuals. Misanthropy may be motivated by feelings of isolation or social alienation, or simply contempt for the prevailing characteristics of humanity.

Overt expressions of misanthropy are common in satire and comedy, although intense misanthropy is generally rare. Subtler expressions are far more common, especially for those pointing out the shortcomings of humanity. In extreme cases, misanthropes may remove themselves from society, becoming hermits, recluses, shut-ins, or suicides.

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